Charmaine DM Royal

Associate Professor in the Department of African and African American Studies

External Address: 
234 Friedl Bldg, Box 90252, Durham, NC 27708-0141
Internal Office Address: 
Duke Box 90252, Durham, NC 27708
Phone: 
(919) 668-6515
Office Hours: 
By appointment

Overview

Charmaine Royal is associate professor of African & African American Studies, Biology, and Community & Family Medicine at Duke University. She is also core faculty in the Duke Initiative for Science and Society, faculty affiliate in the Duke Global Health Institute, and senior fellow in the Kenan Institute for Ethics.

Dr. Royal’s research, scholarship, and teaching focus on ethical and social issues in genetics and genomics on a global scale, particularly the intersection of 'race' and genetics, its policy implications, and practical interventions. She serves on numerous national and international professional committees and boards related to these topics. She directs the Duke Center on Genomics, Race, Identity, Difference (GRID) that aims to inform and transform the concepts, uses, and impacts of 'race' in research, healthcare, and society.

Dr. Royal received a master’s in genetic counseling and a doctorate in human genetics from Howard University. She completed postgraduate training in bioethics and ELSI (ethical, legal, and social implications) research at the National Human Genome Research Institute of the National Institutes of Health, and in epidemiology and behavioral medicine at Howard University Cancer Center.

Education & Training

  • Ph.D., Howard University 1997

  • M.S., Howard University 1992

Green, RC, Christensen, KD, Cupples, LA, Relkin, NR, Whitehouse, PJ, Royal, CDM, Obisesan, TO, Cook-Deegan, R, Linnenbringer, E, Butson, MB, Fasaye, G-A, Levinson, E, Roberts, JS, and REVEAL Study Group, . "A randomized noninferiority trial of condensed protocols for genetic risk disclosure of Alzheimer's disease." Alzheimer's & dementia : the journal of the Alzheimer's Association 11.10 (October 2015): 1222-1230. Full Text

Wonkam, A, Makani, J, Ofori-Aquah, S, Nnodu, OE, Treadwell, M, Royal, C, Ohene-Frempong, K, and Members of the H3Africa Consortium, . "Sickle cell disease and H3Africa: enhancing genomic research on cardiovascular diseases in African patients." Cardiovascular journal of Africa 26.2 Suppl 1 (March 2015): S50-S55. (Review) Full Text

Peprah, E, Xu, H, Tekola-Ayele, F, and Royal, CD. "Genome-wide association studies in Africans and African Americans: expanding the framework of the genomics of human traits and disease." Public health genomics 18.1 (January 2015): 40-51. (Review) Full Text

Wonkam, A, de Vries, J, Royal, CD, Ramesar, R, and Angwafo, FF. "Would you terminate a pregnancy affected by sickle cell disease? Analysis of views of patients in Cameroon." Journal of medical ethics 40.9 (September 2014): 615-620. Full Text

Delaneau, O, Marchini, J, 1000 Genomes Project Consortium, , and 1000 Genomes Project Consortium, . "Integrating sequence and array data to create an improved 1000 Genomes Project haplotype reference panel." Nature communications 5 (June 13, 2014): 3934-. Full Text

Khurana, E, Fu, Y, Colonna, V, Mu, XJ, Kang, HM, Lappalainen, T, Sboner, A, Lochovsky, L, Chen, J, Harmanci, A, Das, J, Abyzov, A, Balasubramanian, S, Beal, K, Chakravarty, D, Challis, D, Chen, Y, Clarke, D, Clarke, L, Cunningham, F, Evani, US, Flicek, P, Fragoza, R, Garrison, E, Gibbs, R, Gümüş, ZH, Herrero, J, Kitabayashi, N, Kong, Y, Lage, K, Liluashvili, V, Lipkin, SM, MacArthur, DG, Marth, G, Muzny, D, Pers, TH, Ritchie, GRS, Rosenfeld, JA, Sisu, C, Wei, X, Wilson, M, Xue, Y, and Yu, F et al. "Integrative Annotation of Variants from 1092 Humans: Application to Cancer Genomics." Science 342.6154 (October 4, 2013): 1235587-1235587. Full Text

Daley, L-AA, Wagner, JK, Himmel, TL, McPartland, KA, Katsanis, SH, Shriver, MD, and Royal, CD. "Personal DNA testing in college classrooms: perspectives of students and professors." Genetic testing and molecular biomarkers 17.6 (June 2013): 446-452. Full Text

1000 Genomes Project Consortium, , Abecasis, GR, Auton, A, Brooks, LD, DePristo, MA, Durbin, RM, Handsaker, RE, Kang, HM, Marth, GT, and McVean, GA. "An integrated map of genetic variation from 1,092 human genomes." Nature 491.7422 (November 2012): 56-65. Full Text

Wagner, JK, and Royal, CD. "Field of genes: an investigation of sports-related genetic testing." Journal of personalized medicine 2.3 (September 12, 2012): 119-137. Full Text

Jonassaint, CR, Ashley-Koch, A, Whitfield, KE, Hoyle, RH, Richman, LS, Siegler, IC, Royal, CD, and Williams, R. "The serotonin transporter gene polymorphism (5HTTLPR) moderates the effect of adolescent environmental conditions on self-esteem in young adulthood: a structural equation modeling approach." Biol Psychol 91.1 (September 2012): 111-119. Full Text Open Access Copy

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